Evolutionary Patterns of Host Plant Use by Delphacid Planthoppers and Their...
AbstractPlanthoppers (Homoptera: Fulgoroidea) are found on every continent except Antarctica and in all major biomes, including tropical rainforests, deserts, grasslands, and the arctic tundra (O’Brien...
View ArticleCharacterisation of five novel zebrafish Eph -related receptor tyrosine...
Abstract Eph-related receptor tyrosine kinases (RTKs) are the largest known subfamily of RTKs, comprising at least a dozen members. Expression studies suggest roles for these genes in patterning and...
View ArticleAnalysis of axon tract formation in the zebrafish brain: the role of...
Abstract. Mutant analysis in the zebrafish is revealing the genes that are expressed in the early neuroepithelium and that regulate factors responsible for the guidance of commissural axons. We review...
View ArticleIdentification of alternatively spliced dab1 isoforms in zebrafish
AbstractWe have investigated the genomic organization, the occurrence of alternative splicing and the differential expression of the zebrafish disabled1 (dab1) gene. Dab1 is a key effector of the...
View ArticleHedgehog signaling patterns the outgrowth of unpaired skeletal appendages in...
AbstractBackgroundLittle is known about the control of the development of vertebrate unpaired appendages such as the caudal fin, one of the key morphological specializations of fishes. Recent analysis...
View ArticleMicroRNAs show a wide diversity of expression profiles in the developing and...
AbstractBackgroundMicroRNA (miRNA) encoding genes are abundant in vertebrate genomes but very few have been studied in any detail. Bioinformatic tools allow prediction of miRNA targets and this...
View ArticleBrain asymmetry is encoded at the level of axon terminal morphology
AbstractBackgroundFunctional lateralization is a conserved feature of the central nervous system (CNS). However, underlying left-right asymmetries within neural circuitry and the mechanisms by which...
View ArticleReduced TFAP2A function causes variable optic fissure closure and retinal...
AbstractMutations in the transcription factor encoding TFAP2A gene underlie branchio-oculo-facial syndrome (BOFS), a rare dominant disorder characterized by distinctive craniofacial, ocular, ectodermal...
View ArticleMorphogenesis underlying the development of the everted teleost telencephalon
AbstractBackgroundAlthough the mechanisms underlying brain patterning and regionalization are very much conserved, the morphology of different brain regions is extraordinarily variable across...
View ArticleCopy number variants in patients with intellectual disability affect the...
AbstractProtein-coding mutations in the transcription factor-encoding gene ARX cause various forms of intellectual disability (ID) and epilepsy. In contrast, variations in surrounding non-coding...
View ArticleLooking to the future of zebrafish as a model to understand the genetic basis...
AbstractIn this brief commentary, we provide some of our thoughts and opinions on the current and future use of zebrafish to model human eye disease, dissect pathological progression and advance in our...
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